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Unveiling the Secrets of Nicotinic Receptors in the Nervous System: A Comprehensive Guide

Jaylen Mitchell

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Published in Nicotinic Receptors In The Nervous System (Frontiers In Neuroscience)

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Nicotinic acetylcholine receptors (nAChRs) are a class of ligand-gated ion channels that play a crucial role in various neurological processes. Their widespread distribution throughout the nervous system underscores their fundamental involvement in a myriad of functions, ranging from synaptic transmission and modulation to neurodevelopment and cognitive processes.

Nicotinic Receptors in the Nervous System (Frontiers in Neuroscience)

by Alchemist Jedi

5 out of 5

Language	:	English
File size	:	7051 KB
Screen Reader	:	Supported
Print length	:	312 pages

This comprehensive guide, "Nicotinic Receptors in the Nervous System: Frontiers in Neuroscience," delves into the multifaceted world of nAChRs, offering an in-depth exploration of their structure, function, and significance in both physiological and pathological contexts. Through a captivating blend of scientific rigor and accessible language, the book unravels the complexities of these remarkable receptors, providing valuable insights for researchers, clinicians, and students alike.

Chapter 1: Unraveling the Structure and Function of nAChRs

The book's inaugural chapter lays the foundation for understanding nAChRs by delving into their intricate structure and functional properties. Readers embark on a journey to discover the molecular architecture of these receptors, unraveling the interplay between their various subunits and the underlying mechanisms that govern their gating and ion permeation. This chapter elucidates the molecular basis for nAChR diversity, highlighting the role of alternative splicing and post-translational modifications.

Chapter 2: nAChRs in Synaptic Transmission and Neuromodulation

Chapter 2 delves into the pivotal role of nAChRs in synaptic communication. It explores their involvement in both excitatory and inhibitory neurotransmission, emphasizing their significance in shaping synaptic plasticity and cognitive functions. The chapter further delves into the diverse roles of nAChRs as modulators of neurotransmitter release, shedding light on their ability to regulate the activity of other ion channels and receptors.

Chapter 3: nAChRs in Neurodevelopment and Cognitive Processes

The third chapter explores the burgeoning field of nAChR involvement in neurodevelopment and cognitive processes. It unravels the molecular mechanisms underlying the role of nAChRs in neuronal survival, synaptogenesis, and neural circuit formation. The chapter also delves into the emerging evidence of nAChR dysfunction in neurodevelopmental disFree Downloads such as autism spectrum disFree Download and schizophrenia.

Chapter 4: nAChRs and Neurological DisFree Downloads

Chapter 4 delves into the pathological aspects of nAChRs, examining their involvement in a wide range of neurological disFree Downloads. It unravels the complex interplay between nAChR dysfunction and diseases such as Alzheimer's disease, Parkinson's disease, and epilepsy. The chapter also explores the therapeutic potential of targeting nAChRs for the treatment of these debilitating conditions.

Chapter 5: Novel Frontiers in nAChR Research

The final chapter ventures into the exciting frontiers of nAChR research, highlighting cutting-edge advancements in understanding their structure, function, and therapeutic potential. It delves into promising new avenues of investigation, including the role of nAChRs in neuroimmune interactions, the development of novel therapeutic agents, and the application of advanced imaging techniques to study nAChR dynamics.

"Nicotinic Receptors in the Nervous System: Frontiers in Neuroscience" concludes with a comprehensive summary of the state-of-the-art knowledge on nAChRs. It emphasizes the remarkable progress made in understanding these essential receptors and their profound influence on neurological function. The book underscores the need for continued research to unravel the complexities of nAChRs and harness their therapeutic potential for the treatment of neurological disFree Downloads.

Nicotinic Receptors in the Nervous System (Frontiers in Neuroscience)

by Alchemist Jedi

5 out of 5